Screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation

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Accuracy of competing-risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation.

OBJECTIVE To examine the diagnostic accuracy of a previously developed model for prediction of pre-eclampsia (PE) by a combination of maternal factors and biomarkers at 11-13 weeks' gestation. METHODS This was a prospective first-trimester multicenter study of screening for PE in 8775 singleton pregnancies. A previously published algorithm was used for the calculation of patient-specific risk...

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Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation: comparison with NICE guidelines and ACOG recommendations.

OBJECTIVE To compare the performance of screening for pre-eclampsia (PE) based on risk factors from medical history, as recommended by NICE and ACOG, with the method proposed by The Fetal Medicine Foundation (FMF), which uses Bayes' theorem to combine the a-priori risk from maternal factors, derived by a multivariable logistic model, with the results of various combinations of biophysical and b...

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Maternal hemodynamics at 11-13 weeks' gestation and risk of pre-eclampsia.

OBJECTIVE Women who develop pre-eclampsia are at increased risk of cardiovascular disease and stroke in the subsequent decades. Individuals with cardiovascular disorders have increased central aortic systolic blood pressure (SBP(Ao) ) and arterial stiffness, as assessed by pulse wave velocity (PWV) and augmentation index (AIx). The aim of this study was to examine the potential value of assessm...

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Maternal plasma soluble endoglin at 11-13 weeks' gestation in pre-eclampsia.

OBJECTIVES To examine the performance of screening for pre-eclampsia (PE) by a combination of maternal factors, soluble endoglin (sEng), pregnancy associated plasma protein-A (PAPP-A), placental growth factor (PlGF) and uterine artery lowest pulsatility index (L-PI) at 11-13 weeks' gestation. METHODS Uterine artery L-PI, sEng, PAPP-A and PlGF were measured at 11-13 weeks in 90 singleton pregn...

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Prediction of Pre-Eclampsia by Maternal Uterine Artery Doppler at 11-14 Weeks of Gestation

Uterine artery doppler is a non-invasive which can be used for prediction of PE and FGE at 20 – 23, but the 11 – 13+6 weeks scan may provide earlier information. This was a prospective observational two year study in a tertiary care center in South India. 330 in low risk, singleton pregnancies were examined between 11–13+6 weeks. In addition to CRL and NT, mean maternal uterine artery PI was me...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics & Gynecology

سال: 2018

ISSN: 0960-7692

DOI: 10.1002/uog.19112